業績（論文）

論文

Toyoshima M, Akamatsu W, Okada Y, Ohnishi T, Balan S, Hisano Y, Iwayama Y, Toyota T, Matsumoto T, Itasaka N, Sugiyama S, Tanaka M, Yano M, Dean B, Okano H, Yoshikawa T, Analysis of induced pluripotent stem cells carrying 22q11.2 deletion Translational Psychiatry 2016 6(11):e934 doi: 10.1038/tp.2016.206
Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, Koya I, Okada Y, Kimura T, Tsuchiya Y, Suzuki S, Onishi N, Kuzumaki N, Matsuzaki Y, Narita M, Ikeda E, Okanoya K, Seino K, Saya H, Okano H, Miura K. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats Nat. Commun 2016 7:11471 DOI: 10.1038/ncomms11471
Ichiyanagi N, Fujimori K, Yano M, Ishihara-Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuiji H, Suzuki N, Warita H, Aoki M, Okano H Establishment of in vitro FUS-associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells Stem Cell Reports 2016.02.011. 6(4):496-510 DOI: 10.1016/j.stemcr.2016.02.011
Shimojo D, Onodera K, Doi-Torii Y, Ishihara Y, Hattori C, Miwa Y, Tanaka S, Okada R, Ohyama M, Shoji M, Nakanishi A, Doyu M, Okano H*, Okada Y* Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells Mol Brain2015 8(1):79 doi: 10.1186/s13041-015-0172-4. *corresponding authors
Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa TInvestigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism Sci Rep 2015 5:16239 doi: 10.1038/srep16239
Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, Mizuno Y, Mochizuki H, Obata F, Okano H. I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway Hum Mol Genet 2015 Sep 24(17):4879-900doi: 10.1093/hmg/ddv212
Andoh-Noda T, Akamatsu W, Miyake K, Matsumoto T, Yamaguchi R, Sanosaka T, Okada Y, Kobayashi T, Ohyama M, Nakashima K, Kurosawa H, Kubota T, Okano HDifferentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineageMolecular Brain 8 312015doi: 10.1186/s13041-015-0121-2
Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudo J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano HLong-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transitionStem Cell Reports 4(3) 360-3732015doi:10.1016/j.stemcr.2015.01.006
Maekawa M, PhD, Yamada K, Toyoshima M, Ohnishi T, Iwayama Y, Shimamoto C, Toyota T, Nozaki Y, Balan S, Matsuzaki H, Iwata Y, Suzuki K, Miyashita M, Kikuchi M, Kato M, Okada Y, Akamatsu W, Norio Mori N, Owada Y, Itokawa M, Okano H, Yoshikawa TUtility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric IllnessesBiological Psychiatry,78(2):116-252015doi: 10.1016/j.biopsych.2014.07.025
Lee H, Lee JK , Park. MH, Hong YR, Marti H , Kim H, Okada Y, Otsu M, Seo E, Park J, Bae JH, Okino N, He X, Schuchman E, Bae J, Jin HKPathological roles of the VEGF/SphK pathway in Niemann-Pick Type C neuronsNat Commu 5:55142014doi: 10.1038/ncomms6514
Numasawa-Kuroiwa Y, Okada Y#, Shibata S, Kishi N, Akamatsu W, Shoji M, Nakanishi A, Oyama M, Osaka H, Inoue K, Takahashi K, Yamanaka S, Kosaki K, Takahashi T, Okano H#Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived OligodendrocytesStem Cell Reports 2 (5) 648-6612014doi: 10.1016/j.stemcr.2014.03.007
#corresponding authors
Kerever A, Mercier F, Nonaka R, de Vega S, Oda Y, Zalc B, Okada Y, Hattori N, Yamada Y, Arikawa-Hirasawa EPerlecan is required for FGF-2 signaling in the neural stem cell nicheStem Cell Res. 1 (2):492-505.2014doi: 10.1016/j.scr.2013.12.009
Bundo M, Toyoshima M, Okada Y, Akamatsu W, Ueda J, Nemoto-Miyauchi T, Sunaga F, Toritsuka M, Ikawa D, Kakita A, Kato M, Kasai K, Kishimoto T, Nawa H, Okano H, Yoshikawa T, Kato T, Iwamoto KIncreased L1 Retrotransposition in the Neuronal Genome in SchizophreniaNeuron.81(2): 306-13,2014doi: 10.1016/j.neuron.2013.10.053
Okano H, Nakamura M, Yoshida K, Okada Y, Tsuji O, Nori S, Ikeda E, Yamanaka S, Miura KSteps toward safe cell therapy using induced pluripotent stem cellsCirculation Research 112(3) 523-33,2013doi: 10.1161/CIRCRESAHA.111.256149
Higurashi N, Uchida T, Christoph L, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori MX, Katsurabayashi S, Shirasaka Y, Okano H, Hirose SA human Dravet syndrome model from patient induced pluripotent stem cellsMol Brain.6(1) , 192013doi:10.1186/1756-6606-6-19
Nihei Y, Ito D, Okada Y, Akamatsu W, Yagi T, Yoshizaki T, Okano H, Suzuki NEnhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophyJ Biol Chem.,288(12):8043-52. 2013doi: 10.1074/jbc.M112.408211
Shofuda T, Kanematsu D, Fukusumi H, Yamamoto A, Bamba Y, Yoshitatsu S, Suemizu H, Nakamura M, Sugimoto Y, Furue KM, Kohara A, Akamatsu W, Okada Y, Okano H, Yamasaki M, Kanemura YHuman Decidua-Derived Mesenchymal Cells are a Promising Source for the Generation and Cell Banking, of Human Induced Pluripotent Stem CellsCell Medicine.4(3), 125-1472013doi:10.3727/215517912X658918
Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, Suematsu M, Yagi T, Ito D, Kosakai A, Hayashi K, Shouji M, Nakanishi A, Suzuki N, Mizuno Y, Mizushima N, Amagai M, Uchiyama Y, Mochizuki H, Hattori N, Okano H Mitochondrial dysfunction associated with increased oxidativestress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue Mol. Brain 2012 5(1) 35 doi: 10.1186/1756-6606-5-35
Kobayashi Y*, Okada Y*, Itakura G, Iwai H, Nishimura S, Nori S, Hikishima K, Konomi T, Fujiyoshi K, Tsuji O, Toyama Y, Yamanaka S, Nakamura M, Okano H Pre-Evaluated Safe Human iPSC-Derived Neural Stem Cells Promote Functional Recovery after Spinal Cord Injury in Common Marmoset without Tumorigenicity PLoS One 2012 7(12): e52787 doi:10.1371/journal.pone.0052787, *equally contributed first authors
Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Suzuki T, Okada Y, Okano HJ, Yamashita JK, Okano H, Narita M Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer PLoS One 2012 7(10): e44368 doi: 10.1371/journal.pone.0044368