業績（論文）

論文

Shimada H, Okada Y#*, Ibata K, Ebise H, Ota S, Tomioka I, Nomura T, Maeda T, Kohda K, Yuzaki M, Sasaki E, Nakamura M, Okano H#* Efficient Derivation of Multipotent Neural Stem/Progenitor Cells from Non-human Primate Embryonic Stem Cells PLoS One 2012 7(11): e49469 *equally contributed last authors, #corresponding authors doi: 10.1371/journal.pone.0049469
Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, Suematsu M, Yagi T, Ito D, Kosakai A, Hayashi K, Shouji M, Nakanishi A, Suzuki N, Mizuno Y, Mizushima N, Amagai M, Uchiyama Y, Mochizuki H, Hattori N, Okano H Mitochondrial dysfunction associated with increased oxidativestress and -synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue Mol. Brain 2012 5(1) 35 doi: 10.1186/1756-6606-5-35
Yagi T, Kosakai A, Ito D, Okada Y, Akamatsu W, Nihei Y, Nabetani A, Ishikawa F, Arai Y, Hirose N, Okano H, Suzuki N Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research PLoS One 2012 7(7):e41572 doi:10.1371/journal.pone.0041572
Muto J, Imai T, Ogawa D, Nishimoto Y, Okada Y, Mabuchi Y, Kawase T, Iwanami A, Mischel PS, Saya H, Yoshida K, Matsuzaki Y, Okano H RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI(3) Kinase/Akt Signaling Pathways PLoS One 2012 7(3):e33431 doi:10.1371/journal.pone.0033431
Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Nagase H, Okada Y, Okano HJ, Yamashita JK, Okano H, Suzuki T, Narita M Effect of κ-opioid receptor agonist on the growth of non-small cell lung cancer (NSCLC) cells Br J Cancer 2012 106(6):1148-52 doi: 10.1038/bjc.2011.574
Nori S*, Okada Y*, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H Grafted human induced pluripotent stem cell-derived neurospheres promotes motor functional recovery after spinal cord injury in mice Proc Natl Acad Sci U S A 2011 108(40):16825-30. *equally contributed first authors doi: 10.1073/pnas.1108077108
Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol. Genet 2011 Sep 13. [Epub ahead of print] 20 (23): 4530-4539 doi: 10.1093/hmg/ddr394
Kawahara H, Okada Y, Imai T, Iwanami A, Mischel PS, Okano H Musashi 1 cooperates in abnormal cell LINeage protein 28 (Lin28)-mediated Let-7 family microRNA biogenesis in early neural differentiation J Biol Chem 2011 Epub 2011 Mar 4 286(18):16121-30. Selected for “Paper of the Week” doi: 10.1074/jbc.M110.199166
Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y Generation of human melanocytes from induced pluripotent stem cells Plos One 2011 6 (1):e16182 doi:10.1371/journal.pone.0016182
Shiozawa S, Kawai K, Okada Y, Tomioka I, Maeda T, Kanda A, Shinohara H, Suemizu H, Okano HJ, Sotomaru Y, Sasaki E, Okano H Gene targeting and subsequent site-specific transgenesis at the β-actin (ACTB) locus in common marmoset embryonic stem cells Stem Cells and Development 2011 Epub 2011 Jan 16 20(9):1587-99 doi:10.1089/scd.2010.0351
Seki T, Yuasa S, Oda M, Egashira T, Yae K, Kusumoto D, Nakata H, Tohyama S, Hashimoto H, Kodaira M, Okada Y, Seimiya H, Fusaki N, Hasegawa M, Fukuda K Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells Cell Stem Cell 2010 7(1):11-4 DOI: 10.1016/j.stem.2010.06.003
Tsuji O, Miura K, Okada Y, Fujiyoshi K, Mukaino M, Nagoshi N, Kitamura K, Kumagai G, Nishino M, Tomisato S, Higashi H, Nagai T, Katoh H, Kohda K, Matsuzaki Y, Yuzaki M, Ikeda E, Toyama Y, Nakamura M, Yamanaka S, Okano H Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury Proc Natl Acad Sci U S A 2010 107(28):12704-9 DOI: 10.1073/pnas.0910106107
Tomioka I, Maeda T, Shimada H, Kawai K, Okada Y, Igarashi H, Oiwa , Iwasaki T, Aoki M, Kimura T, Shiozawa S, Shinohara H, Suemizu H, Sasaki E, Okano H Generating Induced Pluripotent Stem Cells from Common Marmoset (Callithrix jacchus) Fetal Liver Cells using Defined Factors, including Lin28 Genes Cells 2010 15(9):959-69 DOI: 10.1111/j.1365-2443.2010.01437.x
Ishii S, Okada Y, Kadoya T. Matsuzaki Y, Shimazaki T, Okano H Stromal cell-secreted factors promote the survival of ES cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways J. Neurosci. Res 2010 88(4):722-34 DOI: 10.1002/jnr.22250
Tao O, Shimazaki T, Okada Y, Naka H, Kohda K, Yuzaki M, Mizusawa H, Okano H Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells J. Neurosci. Res 2010 1;88(2):234-47 DOI: 10.1002/jnr.22208
Kumagai G, Okada Y, Yamane J, Nagoshi N, Kitamura K, Mukaino M, Tsuji O, Fujiyoshi K, Katoh H, Okada S, Shibata S, Matsuzaki Y, Toh S, Toyama Y, Nakamura M, Okano H Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury Plos One 2009 4(11):e7706 DOI: 10.1371/journal.pone.0007706
Miura K, Okada Y, Aoi T, Okada A, Takahashi K, Okita K, Nakagawa M, Koyanagi M, Tanabe K, Ohnuki M, Ogawa D, Ikeda E, Okano H, Yamanaka S Variation in the safety of induced pluripotent stem cell lines Nat Biotechnol 2009 27(8): 743-745 DOI: 10.1038/nbt.1554
Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, Takahashi K, Homma K, Oyamada N, Inuzuka M, Sonoyama T, Ebihara K, Tamura N, Itoh H, Suemori H, Nakatsuji N, Okano H, Yamanaka S, Nakao K Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells FEBS Lett 2009 18;583(6):1029-33 DOI: 10.1016/j.febslet.2009.02.031
Ogawa D, Okada Y, Nakamura M, Kanemura Y, Okano HJ, Matsuzaki Y, Shimazaki T, Ito M, Ikeda E, Tamiya T, Nagao S, Okano H Evaluation of human fetal neural stem/progenitor cells as a source for cell replacement therapy for neurological disorders: properties and tumorigenicity after long-term in vitro maintenance J. Neurosci.Res 2009 87(2):307-17 DOI: 10.1002/jnr.21843
Okada Y, Matsumoto A., Shimazaki T., Enoki R., Koizumi A., Itoyama Y., Sobue G., Okano H Spatio-temporal recapitulation of central nervous system development in murine ES cell-derived neural stem/progenitor cells Stem Cells 2008 26(12):3086-98 DOI: 10.1634/stemcells.2008-0293