業績（論文）

論文

Akiyama T, Suzuki N, Ishikawa M, Fujimori K, Sone T, Kawada J, Funayama R, Fujishima F, Mitsuzawa S, Ikeda K, Ono H, Shijo T, Osana S, Shirota M, Nakagawa T, Kitajima Y, Nishiyama A, Izumi R, Morimoto S, Okada Y, Kamei T, Nishida M, Nogami M, Kaneda S, Ikeuchi Y, Mitsuhashi H, Nakayama K, Fujii T, Warita H, Okano H, Aoki M. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons EBioMedicine 2019.06.013. Epub 2019 Jun 29 45:362-378 doi: 10.1016/j.ebiom
Yamaoka N, Shimizu K, Imaizumi Y, Ito T, Okada Y, Honda H. Open-Chamber Co-Culture Microdevices for single-cell analysis of skeletal muscle myotubes and motor neurons with neuromuscular junctions BioChip Journal 2019 13(2) 127-132 doi: https://doi.org/10.1007/s13206-018-3202-3
Miyawaki S, Okada Y, Okano H, Miura K, Teratoma Formation Assay for Assessing Pluripotency and Tumorigenicity of Pluripotent Stem Cells Bio-protocol 2017 7(16), e2518 doi: https://doi.org/10.21769/BioProtoc.2518
Nakatsuji H, Araki A, Hashizume A, Hijikata Y, Yamada S, Inagaki T, Suzuki K, Banno H, Suga N, Okada Y, Ohyama M, Nakagawa T, Kishida K, Funahashi T, Shimomura I, Okano H, Katsuno M, Sobue G. Correlation of insulin resistance and motor function in spinal and bulbar muscular atrophy J Neurol 2017 264(5) 839-847 doi: 10.1007/s00415-017-8405-3
Ishigaki S, Fujioka Y, Okada Y, Riku Y, Udagawa T, Honda D, Yokoi S, Endo K, Ikenaka K, Takagi S, Iguchi Y, Sahara N, Takashima A, Okano H, Yoshida M, Warita H, Aoki M, Watanabe H, Okado H, Katsuno M, Sobue G Altered tau isoform ratio caused by loss of Fus and Sfpq function leads to FTLD-like phenotypes Cell Reports 2017 18(5):1118-1131. DOI: 10.1016/j.celrep.2017.01.013
Toyoshima M, Akamatsu W, Okada Y, Ohnishi T, Balan S, Hisano Y, Iwayama Y, Toyota T, Matsumoto T, Itasaka N, Sugiyama S, Tanaka M, Yano M, Dean B, Okano H, Yoshikawa T, Analysis of induced pluripotent stem cells carrying 22q11.2 deletion Translational Psychiatry 2016 6(11):e934 doi: 10.1038/tp.2016.206
Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, Koya I, Okada Y, Kimura T, Tsuchiya Y, Suzuki S, Onishi N, Kuzumaki N, Matsuzaki Y, Narita M, Ikeda E, Okanoya K, Seino K, Saya H, Okano H, Miura K. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats Nat. Commun 2016 7:11471 DOI: 10.1038/ncomms11471
Ichiyanagi N, Fujimori K, Yano M, Ishihara-Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuiji H, Suzuki N, Warita H, Aoki M, Okano H Establishment of in vitro FUS-associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells Stem Cell Reports 2016.02.011. 6(4):496-510 DOI: 10.1016/j.stemcr.2016.02.011
Shimojo D, Onodera K, Doi-Torii Y, Ishihara Y, Hattori C, Miwa Y, Tanaka S, Okada R, Ohyama M, Shoji M, Nakanishi A, Doyu M, Okano H*, Okada Y* Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells Mol Brain2015 8(1):79 doi: 10.1186/s13041-015-0172-4. *corresponding authors
Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa TInvestigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism Sci Rep 2015 5:16239 doi: 10.1038/srep16239
Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, Mizuno Y, Mochizuki H, Obata F, Okano H. I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway Hum Mol Genet 2015 Sep 24(17):4879-900doi: 10.1093/hmg/ddv212
Andoh-Noda T, Akamatsu W, Miyake K, Matsumoto T, Yamaguchi R, Sanosaka T, Okada Y, Kobayashi T, Ohyama M, Nakashima K, Kurosawa H, Kubota T, Okano HDifferentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineageMolecular Brain 8 312015doi: 10.1186/s13041-015-0121-2
Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudo J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano HLong-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transitionStem Cell Reports 4(3) 360-3732015doi:10.1016/j.stemcr.2015.01.006
Maekawa M, PhD, Yamada K, Toyoshima M, Ohnishi T, Iwayama Y, Shimamoto C, Toyota T, Nozaki Y, Balan S, Matsuzaki H, Iwata Y, Suzuki K, Miyashita M, Kikuchi M, Kato M, Okada Y, Akamatsu W, Norio Mori N, Owada Y, Itokawa M, Okano H, Yoshikawa TUtility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric IllnessesBiological Psychiatry,78(2):116-252015doi: 10.1016/j.biopsych.2014.07.025
Lee H, Lee JK , Park. MH, Hong YR, Marti H , Kim H, Okada Y, Otsu M, Seo E, Park J, Bae JH, Okino N, He X, Schuchman E, Bae J, Jin HKPathological roles of the VEGF/SphK pathway in Niemann-Pick Type C neuronsNat Commu 5:55142014doi: 10.1038/ncomms6514
Numasawa-Kuroiwa Y, Okada Y#, Shibata S, Kishi N, Akamatsu W, Shoji M, Nakanishi A, Oyama M, Osaka H, Inoue K, Takahashi K, Yamanaka S, Kosaki K, Takahashi T, Okano H#Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived OligodendrocytesStem Cell Reports 2 (5) 648-6612014doi: 10.1016/j.stemcr.2014.03.007
#corresponding authors
Kerever A, Mercier F, Nonaka R, de Vega S, Oda Y, Zalc B, Okada Y, Hattori N, Yamada Y, Arikawa-Hirasawa EPerlecan is required for FGF-2 signaling in the neural stem cell nicheStem Cell Res. 1 (2):492-505.2014doi: 10.1016/j.scr.2013.12.009
Bundo M, Toyoshima M, Okada Y, Akamatsu W, Ueda J, Nemoto-Miyauchi T, Sunaga F, Toritsuka M, Ikawa D, Kakita A, Kato M, Kasai K, Kishimoto T, Nawa H, Okano H, Yoshikawa T, Kato T, Iwamoto KIncreased L1 Retrotransposition in the Neuronal Genome in SchizophreniaNeuron.81(2): 306-13,2014doi: 10.1016/j.neuron.2013.10.053
Okano H, Nakamura M, Yoshida K, Okada Y, Tsuji O, Nori S, Ikeda E, Yamanaka S, Miura KSteps toward safe cell therapy using induced pluripotent stem cellsCirculation Research 112(3) 523-33,2013doi: 10.1161/CIRCRESAHA.111.256149
Higurashi N, Uchida T, Christoph L, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori MX, Katsurabayashi S, Shirasaka Y, Okano H, Hirose SA human Dravet syndrome model from patient induced pluripotent stem cellsMol Brain.6(1) , 192013doi:10.1186/1756-6606-6-19